Dr. Melanie Saville, Head of Vaccine R&D, CEPI Vaccines:

Presentation: Vaccine development: Where are we?

Replay 27/05/2020



Melanie Saville joined the Coalition for Epidemic Preparedness Innovations (CEPI) in November 2017 initially as Head of Clinical development and now as Director Vaccine Development.

In her role, Melanie leads a technical team who have oversight of the CEPI funded vaccines in development. Melanie is a physician specialized in virology with 20 yrs of experience in the development and licensure of vaccines for the developed and developing world. Over the years, she has contributed to the development and licensure of several vaccines for seasonal and pandemic in uenza, pediatric combinations, Rabies, Japanese Encephalitis and Dengue vaccine in Europe, US and the international area.

Joining Wyeth in 2000 in the UK, Melanie led the phase III clinical development of a live attenuated intranasal in uenza vaccine. In addition, she contributed to several vaccine projects in early development involving adjuvants, immune modulators, viral vectors and conjugate technology.

In 2004 she joined Sano Pasteur in Lyon, France where she initially led the clinical in uenza franchise having oversight of the clinical development of several differentiated seasonal in uenza vaccine and pandemic vaccines. She then led the clinical development of a candidate dengue vaccine moving into phase III. Subsequently she became the Head of Clinical Development for a portfolio of vaccine projects managed out of the EU site. In 2013 she took on a broad role of Chief Medical and Clinical Of cer Dengue having responsibility for the clinical development and licensure of the candidate Dengue vaccine.

In 2016 she joined Janssen Vaccines and prevention in the role of Head Late Development, Clinical and Medical Affairs overseeing several vaccines in development including for Ebola, HIV, RSV and E. coli.

Prior to joining industry, Melanie worked as a clinical virologist and conducted research at the Health Protection Agency (Public Health England) in London in the eld of RSV and HSV.

Melanie obtained her medical degree from University College, London in 1993. She also obtained a Bachelor of Science in Molecular Biology from University College, London and a Masters in Medical Virology from Imperial College, London.