Narcolepsy and Pandemic Influenza Vaccination
What we know and what we need to know before the next Pandemic
March 26-27, 2018
Eurostation II, Place Victor Horta
In partnership with
Federal Agency for Medicines and Health Products (FAMHP)
Vaccine Center of Excellence
This meeting was held under Chatham House Rule
Influenza Pandemics occur when an influenza strain circulates that humans have not been exposed to before. This may lead to widespread circulation and a high case fatality rate.
In 2009 pandemic, several H1N1 vaccines were developed against the new H1N1 virus and were extensively used. In Finland and Sweden an increase in narcolepsy was noted after the mass vaccination with one of these vaccines. Disparate results were seen in other countries with other vaccines. In addition, an increase of narcolepsy has been reported in countries in Asia following wild type influenza infection.
The goal of this meeting is to be prepared for the next pandemic:
- What are the latest data on the risk of narcolepsy following exposure to 2009 pandemic vaccines?
- What scientific data are available and what data are lacking to explain the phenomena that was seen in 2009-10?
- What additional work is needed to prepare for potential use of adjuvanted vaccines for a future pandemic ?